The process of bone growth and breakdown. Imbalances in bone metabolism can lead to conditions like osteoporosis, where bone loss can cause bones to become fragile and more likely to fracture. Risk factors for metabolic bone disease include:
* Vitamin D deficiency
* Being older
* Small body size
* Kidney disease
* Menopause before age 45
* Smoking

Source:

https://www.hopkinsmedicine.org/health/conditions-and-diseases/metabolic-bone-disease